In 1998, when Kate and her family were on their way back from a vacation at JFK airport, this 14 year old beauty caught the eye of Sarah Ducas of Strom Agency. He launched her as a illustrious model. Her first appearance was topless on cover of British magazine, the face. After that her face and body was seen on almost every magazine cover - the Face, Elle, Harper, Arena,Vouge and others.
She appeared in ads for Versace, Yves Saint Laurent, Dolce and Gabbana, Burberry, Calvin Klein and L’Oreal. She made some occasional appearances in movies like Catwalk, Beautopia, Unzipped and Original Copies and television episodes French and Saunders. She has worked with most of the well known photographers in fashion industry as Steven Klein, Mario Testino, Juergen Teller and Mario Sorrenti. She made a come back in modeling after twelve months of cocaine scandal. Holmes has now again contracted with more than 18 brands for ads. In 2006 moss won Model of the Year award at the British Fashion Awards. Moss designed fashion clothing range for Topshop chain and receive mixed reviews. She is very soon going to launch her own perfume.